State laws on generic drug substitution vary widely across the U.S., affecting how pharmacists replace brand-name drugs with generics. Some states require substitution, others require patient consent, and a few block swaps for high-risk medications entirely.
States use copays, pharmacist substitution rules, and preferred drug lists to encourage generic medication use-cutting billions in healthcare costs. But unintended consequences threaten long-term access.
Pharmacists in the U.S. can substitute medications to save costs and improve access, but their legal authority varies by state. Learn how generic and therapeutic substitution rules impact care, safety, and patient outcomes.